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Since the majority of vitamin B12 deficiency diseases have something to do with absorption disorders, injections are the most reliable way of ensuring a supply of this important vitamin: the active ingredient in vitamin B12 shots goes directly into the muscle and thus finds its way into the blood without needing to take the uncertain route through the digestive tract

Neelakantan et al., Biochemical Pharmacology, 2018, gave diet-induced obese mice the compound and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with food intake unchanged (PMID 29155147) [3]